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Evaluation of the effects of pregabalin on chondrocyte proliferation and CHAD, HIF-1α, and COL2A1 gene expression

INTRODUCTION: The aim of the present study is to investigate the effects of pregabalin (PGB) on chondrocyte proliferation and collagen type II (COL2A1), hypoxia-inducible factor 1-α (HIF-1α), and chondroadherin (CHAD) gene expression in osteoarthritic chondrocytes. MATERIAL AND METHODS: Standard pri...

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Détails bibliographiques
Publié dans:Arch Med Sci
Auteurs principaux: Sirin, Duygu Yasar, Karaarslan, Numan
Format: Artigo
Langue:Inglês
Publié: Termedia Publishing House 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6209709/
https://ncbi.nlm.nih.gov/pubmed/30393488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/aoms.2018.73134
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