Simultaneous induction of dispersed and clustered DNA lesions compromises DNA damage response in human peripheral blood lymphocytes

Due to its ability to induce DNA damage in a space and time controlled manner, ionising radiation is a unique tool for studying the mechanisms of DNA repair. The biological effectiveness of ionising radiation is related to the ionisation density which is defined by the linear energy transfer (LET)....

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Cheng, Lei, Brzozowska, Beata, Sollazzo, Alice, Lundholm, Lovisa, Lisowska, Halina, Haghdoost, Siamak, Wojcik, Andrzej
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2018
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6209146/
https://ncbi.nlm.nih.gov/pubmed/30379881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204068
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