Divergent brain gene expression patterns associate with distinct cell-specific tau neuropathology traits in progressive supranuclear palsy

Progressive supranuclear palsy (PSP) is a neurodegenerative parkinsonian disorder characterized by tau pathology in neurons and glial cells. Transcriptional regulation has been implicated as a potential mechanism in conferring disease risk and neuropathology for some PSP genetic risk variants. Howev...

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Pubblicato in:Acta Neuropathol
Autori principali: Allen, Mariet, Wang, Xue, Serie, Daniel J., Strickland, Samantha L., Burgess, Jeremy D., Koga, Shunsuke, Younkin, Curtis S., Nguyen, Thuy T., Malphrus, Kimberly G., Lincoln, Sarah J., Alamprese, Melissa, Zhu, Kuixi, Chang, Rui, Carrasquillo, Minerva M., Kouri, Naomi, Murray, Melissa E., Reddy, Joseph S., Funk, Cory, Price, Nathan D., Golde, Todd E., Younkin, Steven G., Asmann, Yan W., Crook, Julia E., Dickson, Dennis W., Ertekin-Taner, Nilüfer
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2018
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Original Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208732/
https://ncbi.nlm.nih.gov/pubmed/30136084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-018-1900-5
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