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Effect of over expressing protective antigen on global gene transcription in Bacillus anthracis BH500

Protective antigen (PA) of Bacillus anthracis is being considered as a vaccine candidate against anthrax and its production has been explored in several heterologous host systems. Since the systems tested introduced adverse issues such as inclusion body formation and endotoxin contamination, the pro...

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Pubblicato in:Sci Rep
Autori principali: Sharma, Ashish K., Leppla, Stephen H., Pomerantsev, Andrei P., Shiloach, Joseph
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208434/
https://ncbi.nlm.nih.gov/pubmed/30382110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34196-y
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