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Effect of over expressing protective antigen on global gene transcription in Bacillus anthracis BH500

Protective antigen (PA) of Bacillus anthracis is being considered as a vaccine candidate against anthrax and its production has been explored in several heterologous host systems. Since the systems tested introduced adverse issues such as inclusion body formation and endotoxin contamination, the pro...

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Publicado en:Sci Rep
Main Authors: Sharma, Ashish K., Leppla, Stephen H., Pomerantsev, Andrei P., Shiloach, Joseph
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208434/
https://ncbi.nlm.nih.gov/pubmed/30382110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34196-y
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