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Blood handling and leukocyte isolation methods impact the global transcriptome of immune cells

BACKGROUND: Transcriptional profiling with ultra-low input methods can yield valuable insights into disease, particularly when applied to the study of immune cells using RNA-sequencing. The advent of these methods has allowed for their use in profiling cells collected in clinical trials and other st...

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Detalhes bibliográficos
Publicado no:BMC Immunol
Main Authors: Goods, Brittany A., Vahey, Jacqueline M., Steinschneider, Arthur S., Askenase, Michael H., Sansing, Lauren, Christopher Love, J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208098/
https://ncbi.nlm.nih.gov/pubmed/30376808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-018-0268-6
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