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Activated CaMKIIα Binds to the mGlu(5) Metabotropic Glutamate Receptor and Modulates Calcium Mobilization

Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) and metabotropic glutamate receptor 5 (mGlu(5)) are critical signaling molecules in synaptic plasticity and learning/memory. Here, we demonstrate that mGlu(5) is present in CaMKIIα complexes isolated from mouse forebrain. Further in vitro charac...

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Bibliografiske detaljer
Udgivet i:Mol Pharmacol
Main Authors: Marks, Christian R., Shonesy, Brian C., Wang, Xiaohan, Stephenson, Jason R., Niswender, Colleen M., Colbran, Roger J.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207916/
https://ncbi.nlm.nih.gov/pubmed/30282777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.118.113142
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