Helminth-induced IL-4 expands bystander memory CD8(+) T cells for early control of viral infection

Infection with parasitic helminths can imprint the immune system to modulate bystander inflammatory processes. Bystander or virtual memory CD8(+) T cells (T(VM)) are non-conventional T cells displaying memory properties that can be generated through responsiveness to interleukin (IL)-4. However, it...

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Publicat a:Nat Commun
Autors principals: Rolot, Marion, Dougall, Annette M., Chetty, Alisha, Javaux, Justine, Chen, Ting, Xiao, Xue, Machiels, Bénédicte, Selkirk, Murray E., Maizels, Rick M., Hokke, Cornelis, Denis, Olivier, Brombacher, Frank, Vanderplasschen, Alain, Gillet, Laurent, Horsnell, William G. C., Dewals, Benjamin G.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207712/
https://ncbi.nlm.nih.gov/pubmed/30375396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06978-5
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