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Dust mite allergen-specific immunotherapy increases IL4 DNA methylation and induces Der p-specific T cell tolerance in children with allergic asthma

Allergen-specific immunotherapy (allergen-SIT) is a highly effective treatment for children with allergic asthma (AA), an immune-mediated chronic disease leading to bronchial muscle hypertrophy and airway obstruction in response to specific allergens. T helper cells and secreted cytokines play impor...

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Detalhes bibliográficos
Publicado no:Cell Mol Immunol
Main Authors: Wang, Chuang-Ming, Chang, Chia-Bin, Chan, Michael WY, Wen, Zhi-Hong, Wu, Shu-Fen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207658/
https://ncbi.nlm.nih.gov/pubmed/28603280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2017.26
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