The cisplatin-induced lncRNA PANDAR dictates the chemoresistance of ovarian cancer via regulating SFRS2-mediated p53 phosphorylation

As a component of p53-dependent lncRNA (long non-coding RNA), PANDAR (the promoter of CDKN1A antisense DNA damage activated RNA) participates in the epigenetic regulation in human cancer. However, the involvement of PANDAR in cancer chemoresistance is unknown. In this study, we report that PANDAR se...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Wang, Hao, Fang, Lei, Jiang, Jing, Kuang, Ye, Wang, Beidi, Shang, Xiumin, Han, Peilin, Li, Yue, Liu, Meimei, Zhang, Zongfeng, Li, Peiling
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207559/
https://ncbi.nlm.nih.gov/pubmed/30375398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1148-y
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