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Target-Derived Neurotrophic Factors Regulate the Death of Developing Forebrain Neurons after a Change in their Trophic Requirements

Many neurons die as the normal brain develops. How this is regulated and whether the mechanism involves neurotrophic molecules from target cells are unknown. We found that cultured neurons from a key forebrain structure, the dorsal thalamus, develop a need for survival factors including brain-derive...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Lotto, R. Beau, Asavaritikrai, Pundit, Vali, Leila, Price, David J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207345/
https://ncbi.nlm.nih.gov/pubmed/11356878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-11-03904.2001
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