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Target-Derived Neurotrophic Factors Regulate the Death of Developing Forebrain Neurons after a Change in their Trophic Requirements

Many neurons die as the normal brain develops. How this is regulated and whether the mechanism involves neurotrophic molecules from target cells are unknown. We found that cultured neurons from a key forebrain structure, the dorsal thalamus, develop a need for survival factors including brain-derive...

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Publicat a:J Neurosci
Autors principals: Lotto, R. Beau, Asavaritikrai, Pundit, Vali, Leila, Price, David J.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207345/
https://ncbi.nlm.nih.gov/pubmed/11356878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-11-03904.2001
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