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Effect of Intracoronary Metformin on Myocardial Infarct Size in Swine

RATIONALE: Metformin has been demonstrated to decrease infarct size (IS) and prevent post-infarction left ventricular (LV) remodeling in rodents when given intravenously at the time of reperfusion. It remains unclear whether similar cardioprotection can be achieved in a large animal model. OBJECTIVE...

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Publicat a:Circ Res
Autors principals: Techiryan, George, Weil, Brian R., Palka, Beth A., Canty, John M.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207210/
https://ncbi.nlm.nih.gov/pubmed/30355033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.118.313341
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