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Validation of differentially methylated microRNAs identified from an epigenome-wide association study; Sanger and next generation sequencing approaches

OBJECTIVES: Altered DNA methylation and microRNA profiles are associated with diabetic kidney disease. This study compared different sequencing approaches to define the genetic and epigenetic architecture of sequences surrounding microRNAs associated with diabetic kidney disease. RESULTS: We compare...

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Detalhes bibliográficos
Publicado no:BMC Res Notes
Main Authors: Smyth, Laura J., Maxwell, Alexander P., Benson, Katherine A., Kilner, Jill, McKay, Gareth J., McKnight, Amy Jayne
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206874/
https://ncbi.nlm.nih.gov/pubmed/30373632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-018-3872-x
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