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Accelerated DNA methylation changes in middle-aged men define sexual dimorphism in human lifespans

BACKGROUND: Accelerated age-associated DNA methylation changes in males may explain the earlier onset of age-related diseases (e.g., cardiovascular disease (CVD)) and thus contribute to sexually dimorphic morbidity and lifespan. However, the details regarding the emergence of this sex-biased methyla...

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Bibliografski detalji
Izdano u:Clin Epigenetics
Glavni autori: Xiao, Fu-Hui, Chen, Xiao-Qiong, He, Yong-Han, Kong, Qing-Peng
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206726/
https://ncbi.nlm.nih.gov/pubmed/30373676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0573-1
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