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Detection of phosphorothioated (PS) oligonucleotides in horse plasma using a product ion (m/z 94.9362) derived from the PS moiety for doping control

OBJECTIVE: Clinical research on gene therapy has advanced the field of veterinary medicine, and gene doping, which is the illegal use of gene therapy, has become a major concern in horseracing. Since the International Federation of Horseracing Authorities defined the administration of oligonucleotid...

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Dettagli Bibliografici
Pubblicato in:BMC Res Notes
Autori principali: Tozaki, Teruaki, Karasawa, Kaoru, Minamijima, Yohei, Ishii, Hideaki, Kikuchi, Mio, Kakoi, Hironaga, Hirota, Kei-ichi, Kusano, Kanichi, Nagata, Shun-ichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206624/
https://ncbi.nlm.nih.gov/pubmed/30373660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-018-3885-5
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