Linezolid Inhibited Synthesis of ATP in Mitochondria: Based on GC-MS Metabolomics and HPLC Method

Linezolid has been widely used in serious infections for its effective inhibiting effect against multidrug-resistant gram-positive pathogens. However, linezolid caused severe adverse reactions, such as thrombocytopenia, anaemia, optic neuropathy, and near-fatal serotonin syndrome. In order to invest...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Biomed Res Int
Autori principali: Ye, Xuemei, Huang, Aifang, Wang, Xianqin, Wen, Congcong, Hu, Lufeng, Lin, Guanyang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2018
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206563/
https://ncbi.nlm.nih.gov/pubmed/30410924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/3128270
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