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Large-Scale Synonymous Substitutions in Cucumber Mosaic Virus RNA 3 Facilitate Amino Acid Mutations in the Coat Protein

The effect of large-scale synonymous substitutions in a small icosahedral, single-stranded RNA viral genome on virulence, viral titer, and protein evolution were analyzed. The coat protein (CP) gene of the Fny stain of cucumber mosaic virus (CMV) was modified. We created four CP mutants in which all...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Mochizuki, Tomofumi, Ohara, Rie, Roossinck, Marilyn J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206472/
https://ncbi.nlm.nih.gov/pubmed/30185595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01007-18
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