The benefit of minocycline on negative symptoms of schizophrenia in patients with recent-onset psychosis (BeneMin): a randomised, double-blind, placebo-controlled trial

BACKGROUND: The antibiotic minocycline has neuroprotective and anti-inflammatory properties that could prevent or reverse progressive neuropathic changes implicated in recent-onset schizophrenia. In the BeneMin study, we aimed to replicate the benefit of minocycline on negative symptoms reported in...

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Vydáno v:Lancet Psychiatry
Hlavní autoři: Deakin, Bill, Suckling, John, Barnes, Thomas R E, Byrne, Kelly, Chaudhry, Imran B, Dazzan, Paola, Drake, Richard J, Giordano, Annalisa, Husain, Nusrat, Jones, Peter B, Joyce, Eileen, Knox, Emma, Krynicki, Carl, Lawrie, Stephen M, Lewis, Shôn, Lisiecka-Ford, Danuta M, Nikkheslat, Naghmeh, Pariante, Carmine M, Smallman, Richard, Watson, Andrew, Williams, Steven C R, Upthegrove, Rachel, Dunn, Graham
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206257/
https://ncbi.nlm.nih.gov/pubmed/30322824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2215-0366(18)30345-6
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