Maintenance of human haematopoietic stem and progenitor cells in vitro using a chemical cocktail

Identification of effective culture conditions to maintain and possibly expand human HSPCs in vitro is an important goal. Recent advances highlight the efficacy of chemicals in maintaining and converting cell fates. We screened 186 chemicals and found that a combination of CHIR-99021, Forskolin and...

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Publicado en:Cell Discov
Main Authors: Jiang, Mengmeng, Chen, Haide, Lai, Shujing, Wang, Renying, Qiu, Yunfei, Ye, Fang, Fei, Lijiang, Sun, Huiyu, Xu, Yang, Jiang, Xinyi, Zhou, Ziming, Zhang, Tingyue, Li, Yanwei, Xie, Jin, Fang, Qun, Gale, Robert Peter, Han, Xiaoping, Huang, He, Guo, Guoji
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206058/
https://ncbi.nlm.nih.gov/pubmed/30393564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41421-018-0059-5
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