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Engineering induction of singular neural rosette emergence within hPSC-derived tissues

Human pluripotent stem cell (hPSC)-derived neural organoids display unprecedented emergent properties. Yet in contrast to the singular neuroepithelial tube from which the entire central nervous system (CNS) develops in vivo, current organoid protocols yield tissues with multiple neuroepithelial unit...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Knight, Gavin T, Lundin, Brady F, Iyer, Nisha, Ashton, Lydia MT, Sethares, William A, Willett, Rebecca M, Ashton, Randolph Scott
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205811/
https://ncbi.nlm.nih.gov/pubmed/30371350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.37549
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