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Predicting B cell receptor substitution profiles using public repertoire data
B cells develop high affinity receptors during the course of affinity maturation, a cyclic process of mutation and selection. At the end of affinity maturation, a number of cells sharing the same ancestor (i.e. in the same “clonal family”) are released from the germinal center; their amino acid freq...
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| Gepubliceerd in: | PLoS Comput Biol |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6205660/ https://ncbi.nlm.nih.gov/pubmed/30332400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006388 |
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