Long-term polarization of alveolar macrophages to a profibrotic phenotype after inhalation exposure to multi-wall carbon nanotubes

BACKGROUND: Nanomaterials are widely used in various fields. Although the toxicity of carbon nanotubes (CNTs) in pulmonary tissues has been demonstrated, the toxicological effect of CNTs on the immune system in the lung remains unclear. METHODS AND FINDING: In this study, exposure to Taquann-treated...

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Veröffentlicht in:PLoS One
Hauptverfasser: Otsuka, Kunihiro, Yamada, Koichi, Taquahashi, Yuhji, Arakaki, Rieko, Ushio, Aya, Saito, Masako, Yamada, Akiko, Tsunematsu, Takaaki, Kudo, Yasusei, Kanno, Jun, Ishimaru, Naozumi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205598/
https://ncbi.nlm.nih.gov/pubmed/30372450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205702
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