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DSCAM promotes self-avoidance in the developing mouse retina by masking the functions of cadherin superfamily members

During neural development, self-avoidance ensures that a neuron’s processes arborize to evenly fill a particular spatial domain. At the individual cell level, self-avoidance is promoted by genes encoding cell-surface molecules capable of generating thousands of diverse isoforms, such as Dscam1 (Down...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Garrett, Andrew M., Khalil, Andre, Walton, David O., Burgess, Robert W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205498/
https://ncbi.nlm.nih.gov/pubmed/30297418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1809430115
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