C-type lectin receptor LSECtin-mediated apoptotic cell clearance by macrophages directs intestinal repair in experimental colitis

Epithelial barrier disruption is a major cause of inflammatory bowel disease (IBD); however, the cellular and molecular regulation of intestinal epithelial homeostasis remains largely undefined. Here, we show that the C-type lectin receptor LSECtin (Clec4g) on macrophages is required for protection...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Yang, Zaopeng, Li, Qian, Wang, Xin, Jiang, Xuepei, Zhao, Dianyuan, Lin, Xin, He, Fuchu, Tang, Li
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2018
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205441/
https://ncbi.nlm.nih.gov/pubmed/30301800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1804094115
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