Synergism of antihypertensives and cholinesterase inhibitors in Alzheimer's disease

INTRODUCTION: We investigated the effect of antihypertensive (aHTN) medications and cholinesterase inhibitors (ChEIs) on the cognitive decline in patients with Alzheimer's disease (AD) and analyzed synergism by chemogenomics systems pharmacology mapping. METHODS: We compared the effect of aHTN...

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Udgivet i:Alzheimers Dement (N Y)
Main Authors: Hu, Ziheng, Wang, Lirong, Ma, Shifan, Kirisci, Levent, Feng, Zhiwei, Xue, Ying, Klunk, William E., Kamboh, M. Ilyas, Sweet, Robert A., Becker, James, Lv, Qianzhou, Lopez, Oscar L., Xie, Xiang-Qun
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2018
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205113/
https://ncbi.nlm.nih.gov/pubmed/30386819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trci.2018.09.001
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