Efficacy of 5-aminolevulinic acid–based photodynamic therapy against keloid compromised by downregulation of SIRT1-SIRT3-SOD2-mROS dependent autophagy pathway

Keloids exhibit cancer-like properties without spontaneous regression and usually recur post excision. Although photodynamic therapy (PDT) is a promising treatment, details of the mechanisms remain to be elucidated. In this study, we investigated mechanisms involved in 5-Aminolevulinic Acid (5-ALA)–...

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Dettagli Bibliografici
Pubblicato in:Redox Biol
Autori principali: Liu, Tao, Ma, Xiaorong, Ouyang, Tianxiang, Chen, Huiping, Xiao, Yan, Huang, Yingying, Liu, Jun, Xu, Miao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205077/
https://ncbi.nlm.nih.gov/pubmed/30368039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.10.011
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