Human mast cells promote colon cancer growth via bidirectional crosstalk: studies in 2D and 3D coculture models

Chronic inflammation drives the development of colorectal cancer (CRC), where tumor-infiltrating immune cells interact with cancer cells in a dynamic crosstalk. Mast cells (MC), one of earliest recruited immune cells, accumulate in CRC tissues and their density is correlated with cancer progression....

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Yu, Yingxin, Blokhuis, Bart, Derks, Yvonne, Kumari, Sangeeta, Garssen, Johan, Redegeld, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205014/
https://ncbi.nlm.nih.gov/pubmed/30377568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1504729
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