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Molecular mechanism of the synergistic activity of ethambutol and isoniazid against Mycobacterium tuberculosis
Isoniazid (INH) and ethambutol (EMB) are two major first-line drugs for managing tuberculosis (TB), caused by the microbe Mycobacterium tuberculosis. Although co-use of these two drugs is common in clinical practice, the mechanism for the potential synergistic interplay between them remains unclear....
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6204910/ https://ncbi.nlm.nih.gov/pubmed/30185616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002693 |
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