Structural analyses of 4-phosphate adaptor protein 2 yield mechanistic insights into sphingolipid recognition by the glycolipid transfer protein family

The glycolipid transfer protein (GLTP) fold defines a superfamily of eukaryotic proteins that selectively transport sphingolipids (SLs) between membranes. However, the mechanisms determining the protein selectivity for specific glycosphingolipids (GSLs) are unclear. Here, we report the crystal struc...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Ochoa-Lizarralde, Borja, Gao, Yong-Guang, Popov, Alexander N., Samygina, Valeria R., Zhai, Xiuhong, Mishra, Shrawan K., Boldyrev, Ivan A., Molotkovsky, Julian G., Simanshu, Dhirendra K., Patel, Dinshaw J., Brown, Rhoderick E., Malinina, Lucy
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2018
Onderwerpen:
Protein Structure and Folding
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204895/
https://ncbi.nlm.nih.gov/pubmed/30206120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000733
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