From 3D spheroids to tumor bearing mice: efficacy and distribution studies of trastuzumab-docetaxel immunoliposome in breast cancer

PURPOSE: Nanoparticles are of rising interest in cancer research, but in vitro canonical cell monolayer models are not suitable to evaluate their efficacy when prototyping candidates. Here, we developed three-dimensional (3D) spheroid models to test the efficacy of trastuzumab-docetaxel immunoliposo...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Nanomedicine
Hauptverfasser: Rodallec, Anne, Sicard, Guillaume, Giacometti, Sarah, Carré, Manon, Pourroy, Bertrand, Bouquet, Fanny, Savina, Ariel, Lacarelle, Bruno, Ciccolini, Joseph, Fanciullino, Raphaelle
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2018
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204867/
https://ncbi.nlm.nih.gov/pubmed/30425482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S179290
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