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Synthesis of functionalised β-keto amides by aminoacylation/domino fragmentation of β-enamino amides
Ethylenediamine-derived β-enamino amides are used as equivalents of amide enolate synthons in C-acylation reactions with N-protected amino acids. Domino fragmentation of the obtained intermediates leads to functionalised β-keto amides, bearing a protected amino group in their side chain.
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| 發表在: | Beilstein J Org Chem |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Beilstein-Institut
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6204755/ https://ncbi.nlm.nih.gov/pubmed/30410622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.14.238 |
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