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Synthesis of functionalised β-keto amides by aminoacylation/domino fragmentation of β-enamino amides
Ethylenediamine-derived β-enamino amides are used as equivalents of amide enolate synthons in C-acylation reactions with N-protected amino acids. Domino fragmentation of the obtained intermediates leads to functionalised β-keto amides, bearing a protected amino group in their side chain.
Uloženo v:
| Vydáno v: | Beilstein J Org Chem |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Beilstein-Institut
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6204755/ https://ncbi.nlm.nih.gov/pubmed/30410622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.14.238 |
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