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Evaluation of Adenylate Cyclase Toxoid Antigen in Acellular Pertussis Vaccines by Using a Bordetella pertussis Challenge Model in Mice

Bordetella pertussis is the primary causative agent of pertussis (whooping cough), which is a respiratory infection that leads to a violent cough and can be fatal in infants. There is a need to develop more effective vaccines because of the resurgence of cases of pertussis in the United States since...

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Publicado en:Infect Immun
Main Authors: Boehm, Dylan T., Hall, Jesse M., Wong, Ting Y., DiVenere, Andrea M., Sen-Kilic, Emel, Bevere, Justin R., Bradford, Shelby D., Blackwood, Catherine B., Elkins, Cody M., DeRoos, Katherine A., Gray, Mary C., Cooper, C. Garret, Varney, Melinda E., Maynard, Jennifer A., Hewlett, Erik L., Barbier, Mariette, Damron, F. Heath
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204743/
https://ncbi.nlm.nih.gov/pubmed/30012638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00857-17
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