Viable Coxiella burnetii Induces Differential Cytokine Responses in Chronic Q Fever Patients Compared to Heat-Killed Coxiella burnetii

Cytokine responses of chronic Q fever patients to the intracellular bacterium Coxiella burnetii have mostly been studied using ex vivo stimulation of immune cells with heat-killed C. burnetii due to the extensive measures needed to work with viable biosafety level 3 agents. Whether research with hea...

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Udgivet i:Infect Immun
Main Authors: Jansen, Anne F. M., Dinkla, Annemieke, Roest, Hendrik-Jan, Bleeker-Rovers, Chantal P., Schoffelen, Teske, Joosten, Leo A. B., Wever, Peter C., van Deuren, Marcel, Koets, Ad P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Bacterial Infections
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204733/
https://ncbi.nlm.nih.gov/pubmed/30037794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00333-18
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