MrpJ Directly Regulates Proteus mirabilis Virulence Factors, Including Fimbriae and Type VI Secretion, during Urinary Tract Infection

Proteus mirabilis is a leading cause of catheter-associated urinary tract infections (CAUTIs) and urolithiasis. The transcriptional regulator MrpJ inversely modulates two critical aspects of P. mirabilis UTI progression: fimbria-mediated attachment and flagellum-mediated motility. Transcriptome data...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Debnath, Irina, Stringer, Anne M., Smith, Sara N., Bae, Emily, Mobley, Harry L. T., Wade, Joseph T., Pearson, Melanie M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
Schlagworte:
Bacterial Infections
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204732/
https://ncbi.nlm.nih.gov/pubmed/30082479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00388-18
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