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Effect of Hypoxia on the Pathogenesis of Acinetobacter baumannii and Pseudomonas aeruginosa In Vitro and in Murine Experimental Models of Infection

Hypoxia modulates bacterial virulence and the inflammation response through hypoxia-inducible factor 1α (HIF-1α). Here we study the influence of hypoxia on Acinetobacter baumannii and Pseudomonas aeruginosa infections. In vitro, hypoxia increases the bactericidal activities of epithelial cells again...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Gil-Marqués, María Luisa, Pachón-Ibáñez, María Eugenía, Pachón, Jerónimo, Smani, Younes
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204731/
https://ncbi.nlm.nih.gov/pubmed/30082478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00543-18
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