Lipid A Remodeling Is a Pathoadaptive Mechanism That Impacts Lipopolysaccharide Recognition and Intracellular Survival of Burkholderia pseudomallei

Burkholderia pseudomallei causes the severe disease melioidosis. The bacterium subverts the host immune system and replicates inside cells, and host mortality results primarily from sepsis-related complications. Lipopolysaccharide (LPS) is a major virulence factor and mediator of sepsis that many pa...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Norris, Michael H., Somprasong, Nawarat, Schweizer, Herbert P., Tuanyok, Apichai
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204721/
https://ncbi.nlm.nih.gov/pubmed/30037795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00360-18
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