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ENPP1-Fc prevents neointima formation in generalized arterial calcification of infancy through the generation of AMP

Generalized arterial calcification of infancy (GACI) is associated with widespread arterial calcification and stenoses and is caused by mutations in ENPP1. ENPP1 encodes for ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1), which cleaves ATP to generate inorganic pyrophosphate (PP(i)) and...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Exp Mol Med
Päätekijät: Nitschke, Yvonne, Yan, Yan, Buers, Insa, Kintziger, Kristina, Askew, Kim, Rutsch, Frank
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204430/
https://ncbi.nlm.nih.gov/pubmed/30369595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-018-0163-5
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