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ENPP1-Fc prevents neointima formation in generalized arterial calcification of infancy through the generation of AMP
Generalized arterial calcification of infancy (GACI) is associated with widespread arterial calcification and stenoses and is caused by mutations in ENPP1. ENPP1 encodes for ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1), which cleaves ATP to generate inorganic pyrophosphate (PP(i)) and...
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| Publicado no: | Exp Mol Med |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6204430/ https://ncbi.nlm.nih.gov/pubmed/30369595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-018-0163-5 |
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