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Vildagliptin Attenuates Hepatic Ischemia/Reperfusion Injury via the TLR4/NF-κB Signaling Pathway

The Toll-like receptor-4 (TLR4)/nuclear factor kappa B (NF-κB) signaling pathway is vital in the pathogenesis of hepatic ischemia/reperfusion (HIR) injury. Dipeptidyl peptidase-4 (DPP4) inhibitors exert protective effects on IR injury of the kidney, heart, and lung; however, their effect on the live...

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Détails bibliographiques
Publié dans:Oxid Med Cell Longev
Auteurs principaux: Sherif, Iman O., Al-Shaalan, Nora H.
Format: Artigo
Langue:Inglês
Publié: Hindawi 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204182/
https://ncbi.nlm.nih.gov/pubmed/30405876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/3509091
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