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Clinicopathological and prognostic correlations of HER3 expression and its degradation regulators, NEDD4–1 and NRDP1, in primary breast cancer

BACKGROUND: Human epidermal growth factor receptor HER3 (ErbB3), especially in association with its relative HER2 (ErbB2), is known as a key oncogene in breast tumour biology. Nonetheless, the prognostic relevance of HER3 remains controversial. NEDD4–1 and NRDP1 are signalling molecules closely rela...

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Bibliografiske detaljer
Udgivet i:BMC Cancer
Main Authors: Luhtala, Satu, Staff, Synnöve, Kallioniemi, Anne, Tanner, Minna, Isola, Jorma
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204010/
https://ncbi.nlm.nih.gov/pubmed/30367623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4917-1
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