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Kilobase Pair Chromatin Fiber Contacts Promoted by Living-System-Like DNA Linker Length Distributions and Nucleosome Depletion

Nucleosome placement, or DNA linker length patterns, are believed to yield specific spatial features in chromatin fibers, but details are unknown. Here we examine by mesoscale modeling how kilobase (kb) range contacts and fiber looping depend on linker lengths ranging from 18–45 bp, with values mode...

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Bibliographic Details
Published in:J Phys Chem B
Main Authors: Bascom, Gavin D, Kim, Taejin, Schlick, Tamar
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203935/
https://ncbi.nlm.nih.gov/pubmed/28299939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.7b00998
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