Spatiotemporal regulation of the GPCR activity of BAI3 by C1qL4 and Stabilin-2 controls myoblast fusion

Myoblast fusion is tightly regulated during development and regeneration of muscle fibers. BAI3 is a receptor that orchestrates myoblast fusion via Elmo/Dock1 signaling, but the mechanisms regulating its activity remain elusive. Here we report that mice lacking BAI3 display small muscle fibers and i...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Hamoud, Noumeira, Tran, Viviane, Aimi, Takahiro, Kakegawa, Wataru, Lahaie, Sylvie, Thibault, Marie-Pier, Pelletier, Ariane, Wong, G. William, Kim, In-San, Kania, Artur, Yuzaki, Michisuke, Bouvier, Michel, Côté, Jean-François
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203814/
https://ncbi.nlm.nih.gov/pubmed/30367035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06897-5
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