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The added value of genetic information in colorectal cancer risk prediction models: development and evaluation in the UK Biobank prospective cohort study

Colorectal cancer (CRC) risk prediction models could be used to risk-stratify the population to provide individually tailored screening provision. Using participants from the UK Biobank prospective cohort study, we evaluated whether the addition of a genetic risk score (GRS) could improve the perfor...

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Pubblicato in:Br J Cancer
Autori principali: Smith, Todd, Gunter, Marc J., Tzoulaki, Ioanna, Muller, David C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203780/
https://ncbi.nlm.nih.gov/pubmed/30323197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0282-8
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