Therapeutic effects of favipiravir against severe fever with thrombocytopenia syndrome virus infection in a lethal mouse model: Dose-efficacy studies upon oral administration

Severe fever with thrombocytopenia syndrome (SFTS), caused by SFTS virus (SFTSV), is a viral hemorrhagic fever with a high case fatality rate. Favipiravir was reported to be effective in the treatment of SFTSV infection in vivo in type I interferon receptor knockout (IFNAR(−/−)) mice at treatment do...

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Veröffentlicht in:PLoS One
Hauptverfasser: Tani, Hideki, Komeno, Takashi, Fukuma, Aiko, Fukushi, Shuetsu, Taniguchi, Satoshi, Shimojima, Masayuki, Uda, Akihiko, Morikawa, Shigeru, Nakajima, Nozomi, Furuta, Yousuke, Saijo, Masayuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203377/
https://ncbi.nlm.nih.gov/pubmed/30365543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0206416
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