CD25 and TGF-β blockade based on predictive integrated immune ratio inhibits tumor growth in pancreatic cancer

BACKGROUND: The prognosis of pancreatic ductal adenocarcinoma (PDAC) remains poor due to the difficulty of disease diagnosis and therapy. Immunotherapy has had robust performance against several malignancies, including PDAC. In this study, we aim to analyze the expression of CD8 and FoxP3 on T lymph...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Pu, Ning, Zhao, Guochao, Yin, Hanlin, Li, Jian-ang, Nuerxiati, Abulimiti, Wang, Dansong, Xu, Xuefeng, Kuang, Tiantao, Jin, Dayong, Lou, Wenhui, Wu, Wenchuan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203282/
https://ncbi.nlm.nih.gov/pubmed/30359281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1673-6
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