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The miR-503 cluster is coordinately under-expressed in endometrial endometrioid adenocarcinoma and targets many oncogenes, cell cycle genes, DNA repair genes and chemotherapy response genes

BACKGROUND: The miR-503 miRNA cluster, located at Xq23.1, is composed of six miRNAs; miR-424, miR-503, miR-542, miR-450a-1, miR-450a-2 and miR-450b. Numerous studies have focused on the relationship of one or two members of the cluster and various human cancers. Here, we suggest that the entire clus...

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Publicat a:Onco Targets Ther
Autors principals: Devor, Eric J, Cha, Elizabeth, Warrier, Akshaya, Miller, Marina D, Gonzalez-Bosquet, Jesus, Leslie, Kimberly K
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203085/
https://ncbi.nlm.nih.gov/pubmed/30425513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S180921
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