Knockdown of insulin-like growth factor 1 exerts a protective effect on hypoxic injury of aged BM-MSCs: role of autophagy

BACKGROUND: Treatment with bone marrow mesenchymal stem cells (BM-MSCs) has been demonstrated to be an excellent cellular-based therapeutic strategy for treating myocardial infarction (MI). However, most of the patients suffering with MI are elderly. Hypoxic conditions can cause apoptosis of BM-MSCs...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Yang, Ming, Wen, Tong, Chen, Haixu, Deng, Jingyu, Yang, Chao, Zhang, Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202872/
https://ncbi.nlm.nih.gov/pubmed/30359321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-1028-5
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