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Computational Simulations of Thrombolytic Therapy in Acute Ischaemic Stroke

Ischaemic stroke can occur when an artery to the brain is blocked by a blood clot. The use of thrombolytic agents, such as tissue plasminogen activator (tPA), to dissolve the occluding clot is limited by the risk of intracerebral haemorrhage (ICH), a known side effect associated with tPA. We develop...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Piebalgs, Andris, Gu, Boram, Roi, Dylan, Lobotesis, Kyriakos, Thom, Simon, Xu, Xiao Yun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202379/
https://ncbi.nlm.nih.gov/pubmed/30361673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34082-7
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