Autophagy modulates temozolomide-induced cell death in alveolar Rhabdomyosarcoma cells

Rhabdomyosarcoma (RMS) is a muscle-derived tumor. In both pre-clinical and clinical studies Temozolomide (TMZ) has been recently tested against RMS; however, the precise mechanism of action of TMZ in RMS remains unclear. Here we demonstrate that TMZ decreases the cell viability of the RH30 RMS and C...

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Pubblicato in:Cell Death Discov
Autori principali: Moghadam, Adel Rezaei, da Silva Rosa, Simone C., Samiei, Ehsan, Alizadeh, Javad, Field, Jared, Kawalec, Philip, Thliveris, James, Akbari, Mohsen, Ghavami, Saeid, Gordon, Joseph W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202374/
https://ncbi.nlm.nih.gov/pubmed/30416757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-018-0115-9
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