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Mesopontine cholinergic inputs to midbrain dopamine neurons drive stress-induced depressive-like behaviors

Stressful life events are primary environmental factors that markedly contribute to depression by triggering brain cellular maladaptations. Dysregulation of ventral tegmental area (VTA) dopamine neurons has been causally linked to the appearance of social withdrawal and anhedonia, two classical mani...

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Foilsithe in:Nat Commun
Main Authors: Fernandez, Sebastian P., Broussot, Loïc, Marti, Fabio, Contesse, Thomas, Mouska, Xavier, Soiza-Reilly, Mariano, Marie, Hélène, Faure, Philippe, Barik, Jacques
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202358/
https://ncbi.nlm.nih.gov/pubmed/30361503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06809-7
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