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Targeting p75 neurotrophin receptors ameliorates spinal cord injury-induced detrusor sphincter dyssynergia in mice

AIMS: To determine the role of p75 neurotrophin receptor (p75(NTR)) and the therapeutic effect of the selective small molecule p75(NTR) modulator, LM11A-31, in spinal cord injury (SCI) induced lower urinary tract dysfunction (LTUD) using a mouse model. METHODS: Adult female T(8)-T(9) transected mice...

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Detalhes bibliográficos
Publicado no:Neurourol Urodyn
Main Authors: Zabbarova, Irina V., Ikeda, Youko, Carder, Evan J., Wipf, Peter, Wolf-Johnston, Amanda S., Birder, Lori A., Yoshimura, Naoki, Getchell, Samuel E., Almansoori, Khalifa, Tyagi, Pradeep, Fry, Christopher H., Drake, Marcus J., Kanai, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202156/
https://ncbi.nlm.nih.gov/pubmed/29806700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nau.23722
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