The novel mechanism of anticancer effect on gastric cancer through inducing G0/G1 cell cycle arrest and caspase-dependent apoptosis in vitro and in vivo by methionine enkephalin

BACKGROUND: Gastric cancer (GC) is the second cause of cancer-related deaths. Methionine enkephalin (MENK), an endogenous opioid peptide, has immunological and antitumor activity. PURPOSE: The aim of this work was to investigate whether MENK could exhibit activity against human GC in vitro and in vi...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Wang, Xiaonan, Tian, Jing, Jiao, Xue, Geng, Jin, Wang, Reizhe, Liu, Ning, Gao, Xinghua, Griffin, Noreen, Gao, Yuan, Shan, Fengping
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201847/
https://ncbi.nlm.nih.gov/pubmed/30425572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S178343
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